ZHU Qingxia, XU Qiongqiong, LIU xin

(Jingdezhen Ceramic Institute, Jingdezhen 333001)

Abstract:Carbonated hydroxyapatite (CHA) was prepared by the wet chemical method. The effect of carbonate substitution on the structure and surface energy was studied. The cell attachment and proliferation behavior of CHA and Hydroxyapatite (HA) were compared by the cell culture experiments. The relation between surface energy and cell compatibility was investigated. The change of crystal structure was characterized by X -ray diffraction and Fourier transform infrared spectroscopy, and the contact angle was measured to calculate the surface energy. The results show that the substitution giving priority to B -type occurs almost exclusively via aqueous precipitation reactions in an alkali medium. The polar component of surface energy of B-type CHA is higher than that of HA. Osteoblastic cell attach and proliferate very well on the surface, which indicates the excellent cell compatibility.

Keywords:carbonated hydroxyapatite, cell compatibility, surface energy, crystal structure